Experiment 1057121
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Empty organism |
| Citation | DORLING,P: HUXTABLE,C: DI BELLO,IC: WINCHESTER,B:. (1983). SWAINSONINE-INDUCED MANNOSIDOSIS: REVERSIBLE CHEMICALLY INDUCIBLE PHENOCOPY OF AN INHERITED DISORDER.. 11(6) |
| Amount utilized | |
| Compound isolated | |
| Disease | THERE WAS AN INCREASE IN INTRACELLULAR ACCUMULATION OF MANNOSE RICH OLIGOSACCHARIDES IN THE CELLS.RESULTS INDICATE THAT GOLGI A-D-MANOSIDASE WAS INHIBITED.THE CONDITION WAS SIMILAR TO GENETIC MANNOSIDOSIS. |
| Dose amount | 100.0 MG |
| Number | 4 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | CONC USED |