Experiment 1065504

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODEPREPARATION OF DERIVATIVES OFSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

VINDESINE*

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismCatharanthus roseus (APOCYNACEAE)
CitationCONRAD,RA: CULLINAN,GJ: GERZON,K: POORE,GA:. (1979). STRUCTURE-ACTIVITY RELATIONSHIPS OF DIMERIC CATHARANTHUS ALKALOID. 2. EXPERIMENTAL ANTITUMOR ACTIVITITES OF N-SUBSTITUTED DEACETYLVINBLASTINE AMIDE (VINDESINE) SULFATES.. 22()
Amount utilized
Compound isolated
DiseaseDAILY DOSING FOR 8-10 DAYS
Dose amount0.10 MG
Number1
Percent yield60%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultTWD