Experiment 1066503

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

LEUROCRISTINE

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismCatharanthus roseus (APOCYNACEAE)
CitationROSNER,F: HIRSHAUT,Y: GRUNWALD,HW: DEUTSCH,S:. (1978). POTENTIATION OF VINCRISTINE CYTOTOXICITY BY HORMONES: CORTICOSTEROIDS, ANDROGENS, ESTROGENS AND PROGESTINS.. 5()
Amount utilized
Compound isolated
DiseaseCYTOTOXIC AT THIS CONCENTRATION AFTER ADDITION OF 2.8 MCG/ML OF PREDNISOLONE OTHER STEROIDS PRODUCE A SIMILAR POTENTIATION OF CYTOTOXICITY
Dose amount12.8 NG
Number2
Qualitative resultINACTIVE
AnimalCELL CULTURE
Per unitML
Dose expressionCONC USED