Experiment 1072274
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Catharanthus roseus (APOCYNACEAE) |
| Citation | SKLAROFF,RB: STRAUS,D: YOUNG,C:. (1979). PHASE II TRIAL OF VINDESINE IN PATIENTS WITH MALIGNANT LYMPHOMA.. 63() |
| Amount utilized | |
| Compound isolated | |
| Disease | A PHASE II STUDY IN 43 PATIENTS WITH MALIGNANT LYMPHOMA DOSING WAS WEEKLY 1/43 COMPLETE REMISSIONS:4/43 PARTIAL REMISSIONS MYELOSUPPRESSIN WAS THE DOSE-LIMITING TOXIC EFFECT(PRINCIPALLY LEUKOPENIA) |
| Dose amount | 2-4.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |