Experiment 1072293
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Catharanthus roseus (APOCYNACEAE) |
| Citation | SKLAROFF,RB: ARLIN,Z: YOUNG,CW:. (1979). PHASE II TRIAL OF VINDESINE IN PATIENTS WITH ACUTE LEUKEMIA.. 63() |
| Amount utilized | |
| Compound isolated | |
| Disease | A PHASE II TRIAL IN 18 PATIENTS WITH ACUTE LEUKEMIA WHO HAD FAILED CONVENTIONAL CHEMOTHERAPY DOSING WAS BY IV BOLUS INFUSION DAILY X 5-10 DAYS SIGNIFICANT HEMATOLOGIC TOXICITY |
| Dose amount | 1-2.0 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |