Experiment 1075985

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

LATHYROL,6-17-EPOXY:

Details

PropertyValue
Pharmacology
TUMOR PROMOTING EFFECT
Administration routeIP
OrganismEmpty organism
CitationARMUTH,V: BERENBLUM,I: ADOLF,W: OPFERKUCH,HJ: SCHMIDT,R: SORG,B: HECKER,E:. (1979). SYSTEMIC PROMOTING ACTION AND LEUKEMOGENESIS IN SWR MICE BY PHORBOL AND STRUCTURALLY RELATED POLYFUNCTIONAL DITERPENES.. 95()
Amount utilized
Compound isolated
DiseaseANIMALS WERE GIVEN 15 MCG OF DIMETHYLNITROSAMINE(S.C.)DURING THE FIRST 24 HOURS AFTER BIRTH. THE TEST COMPOUND WAS THEN GIVEN TWICE WEEKLY FOR NINE MONTHS.
Dose amount0.5 MICROMOLS
Number1
Qualitative resultACTIVE
AnimalMOUSE
Per unitANIMAL
Dose expressionDOSE
GenderFEMALE