Experiment 1078674
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Empty organism |
| Citation | ZATUCHNI,GI: OSBORN,CK:. (1981). GOSSYPOL: A POSSIBLE MALE ANTIFERTILITY AGENT. REPORT OF A WORKSHOP.. 1(4) |
| Amount utilized | |
| Compound isolated | |
| Disease | DAILY DOSEING FOR 12 WEEKS. SPERM CONCENTRATION MUCH REDUCED:NON-MOTILE, ABNORMAL SPERM IN CAUDA EPIDIDYMIDES:SPERM BROKEN, SPERM HEADS SEPARATED FROM TAILS, TAILS SHARPLY BENT:MATING NORMAL: SERUM LH, FSH, T NORMAL. MAJORITY OF RATS INFERTILE:RETURN TO FERTILITY SLOW(12 WEEKS POST-TREATMENT). |
| Dose amount | 7.5 MG |
| Number | 6 |
| Qualitative result | INACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |
| Gender | MALE |