Experiment 1085822

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)COMPLETE SYNTHESIS REPORTEDSTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

TIGLIA-1-6-DIEN-3-ONE,15-16-17-TRINOR-4-9-20-TRIHYDROXY-13-ALPHA-TETRADECANOYL-OXY:

Details

PropertyValue
Pharmacology
IRRITANT ACTIVITY
Administration routeGASTRIC INTUBATION
OrganismEmpty organism
CitationSORG,B: GSCHWENDT,M: THIELMANN,HW: HECKER,E:. (1980). STRUCTURE ACTIVITY RELATIONSHIPS OF POLYFUNCTIONAL DITERPENES OF THE TIGLIANE TYPE. IV.DERIVATIVES OF TIGLIANE WITHOUT OR WITH OPENED CYCLOPROPANE RING AND THEIR IRRITANT AND PROMOTING ACTIVITY.. 35()
Amount utilized
Compound isolated
Dose amount>100 NANOMOLS
Number1
Qualitative resultINACTIVE
AnimalMOUSE
Per unitEAR
Dose expressionID50(4 HR)