Experiment 1088317
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | CREAGAN,ET: AHMANN,DL: SCHUTT,AJ: GREEN,SJ:. (1982). PHASE II STUDY OF THE COMBINATION OF VINBLASTINE, BLEOMYCIN, AND CISPLATIN IN ADVANCED MALIGNANT MELANOMA.. 66() |
| Amount utilized | |
| Compound isolated | |
| Disease | A PHASE II CLINICAL STUDY IN 18 PATIENTS WITH DISSEMINATED MALIGNANT MELANOMA WITH A MONTHLY REGIMEN OF VINCALEUKOBLASTINE,BLEOMYCIN AND CISPLATIN. 17 PATIENTS HAD HAD NO PRIOR CHEMOTHERAPY AND 12 HAS PREDOMINANTLY VISCERAL DISEASE. AN 11% RESPONSE RATE CONCOMITANT WITH SUBSTANTIAL GASTROINTESTINAL AND HEMATOLOGICAL TOXIC EFFECT WAS ACHEIVED. |
| Dose amount | 6.0 MG |
| Number | 1 |
| Qualitative result | WEAK ACTIVITY |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |
| Gender | GIVEN TO BOTH SEXES |