Experiment 1096030
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Dieffenbachia picta (ARACEAE) |
| Citation | LADEIRA,AM: ANDRADE,SO: SAWAYA,P:. (1975). STUDIES ON DIEFFENBACHIA PICTA. TOXIC EFFECTS IN GUINEA PIGS.. 34() |
| Amount utilized | |
| Compound isolated | |
| Disease | TESTS WERE CARRIED OUT ON FRESH MATERIAL SINCE THE JUICE LOST ACTIVITY EVEN WHEN REFRIGERATED. STEM JUICE WAS FRACTIONATED BY CENTRIFUGATION(10,000 RPM AT 3 C/1 HOUR) AND THE PRECIIPITATE WAS USED FOR TESTING. ALL EIGHT ANIMALS WERE DEAD AFTER 24 HOURS. ACTIVITY WAS UNSTABLE TO HEATING AT 100 C FOR FIVE MINUTES AND TO DRYING AT 50-60 C. PRETREATMENT WITH ANTIHISTAMINE DID NOT ALTER THE EFFECTS. INCUBATION OF THE TEST SUBSTANCE WITH CHYMOTRYPSIN DID NOT ALTER THE EFFECTS. |
| Dose amount | 0.4 ML |
| Number | 5 |
| Animal | GUINEA PIG |
| Per unit | ANIMAL |
| Dose expression | DOSE |
| Extract | JUICE |