Experiment 1097491

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOCARCINOGENIC DATA (MARKER CODE)STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

INGENOL-3-5-20-TRIACETATE

Details

PropertyValue
Pharmacology
TUMOR PROMOTING EFFECT
Administration routeEXTERNAL
OrganismEuphorbia ingens (EUPHORBIACEAE)
CitationOPFERKUCH,HJ: HECKER,E:. (1982). ON THE ACTIVE PRINCIPLES OF THE SPURGE FAMILY (EUPHORBIACEAE). 4. SKIN IRRITANT AND TUMOR PROMOTING DITERPENE ESTERS FROM EUPHORBIA INGENS.. 103()
Amount utilized
Compound isolated
DiseaseINITIATOR WAS DMBA. FORMATION OF MALIGNANT CARCINOMAS.
Dose amount50.0 NANOMOLS
Number6
Qualitative resultACTIVE
AnimalMOUSE
Per unitANIMAL
Dose expressionDOSE