Experiment 1116839
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Empty organism |
| Citation | BARAM,NI: PAIZIEVA,RZ: ISMAILOVA,AI: LAGUTKIN,NA: MITIN,NN: ZUBAIROV,MM: ARKHIPOVA,GN: PETRACHEVA,GK:. (1981). ANTIVIRAL ACTIVITY OF SEVERAL DERIVATIVES OF GOSSYPOL AND OTHER ALDEHYDES.. () |
| Amount utilized | |
| Compound isolated | |
| Disease | 15 ALDEHYDES,INCLUDING GOSSYPOL,WERE TESTED FOR ANTIVIRAL ACTIVITY. WHEN ADMINISTERED TO MICE AT 25-30 MCG/KG,THE COMPOUNDS PROTECTED 10-32.7% OF THE ANIMALS AGAINST INFECTION. STRUCTURE-ACTIVITY RELATIONSHIPS ARE DISCUSSED. |
| Dose amount | 25-30 MCG |
| Number | 5 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |