Experiment 1133092

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF EXTRACT - IN VIVO

Alerts

HISTOPATHOLOGY DATA ARE PRESENTED AND DISCUSSED.EFFECTS DESCRIBED ARE FROM A MULTI-COMPONENT RX.

Details

PropertyValue
Pharmacology
WEIGHT INCREASE
Administration routeGASTRIC INTUBATION
OrganismPaeonia albiflora (PAEONIACEAE)
CitationABE,H: YASUDA,Y: SAKAGUCHI,M: ARICHI,S: ODASHIMA,S:. (1980). PHARMACOLOGICAL STUDIES ON PRESCRIPTION CONTAINING BUPLEURI RADIX.I. EFFECTS ON WEIGHTS OF VARIOUS ORGANS AND HISTOLOGICAL CHANGES.. 100()
Amount utilized
Compound isolated
DiseaseA MULTICOMPONENT PRESCRIPTION CONTAINING BUPLEURA FALCATUM (ROOT), SCUTELLARIA BAICALENSIS (ROOT), PANAX GINSENG (ROOT), GLYCYRRHIZA URALENSIS (ROOT), ZINGIBER OFFICINALE (RHIZOME), PAEONIA ALBIFLORA (ROOT), RHEUM PALMATUM (RHIZOME). CINNAMOMUM SPECIES (BARK), PINELLIA TERNATA (TUBERS), ZIZYPHUS SPECIES (FRUIT), AND CITRUS SPECIES (UNRIPE FRUIT). TREATED RATS GAINED WEIGHT FASTER THAN CONTROLS. THERE WAS INCREASED ADRENAL WEIGHT, BUT NO CHANGE IN LIVER OR SPLEEN.
Dose amountVAR
Number2
Qualitative resultACTIVE
AnimalRAT
Dose expressionDOSE
ExtractH2O EXT