Experiment 1134763

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

BOUVARDIN

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationADWANKAR,MK: KHANDALEKAR,DD: CHITNIS,MP:. (1984). COMBINATION CHEMOTHERAPY OF EARLY AND ADVANCED MURINE P388 LEUKAEMIA WITH BOUVARDIN, CIS-DIAMMINEDICHLOROPLATINUM AND VINCRISTINE.. 41(5)
Amount utilized
Compound isolated
DiseaseGIVEN ON DAY 5 ONLY WITH LEUROCRISTINE 1.0 MG/KG, 2.0 MG/KG.
Dose amount2.0 MG
Number5
Percent yield35%
Qualitative resultWEAK ACTIVITY
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS