Experiment 1134804

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODESTRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODE

Compounds isolated

INGENOL,3-O-DODECA-2-4-6-8-TETRAENOYL:INGENOL,3-O-DECA-2-4-6-TRIENOYL:

Details

PropertyValue
Pharmacology
IRRITANT ACTIVITY
Administration routeEXTERNAL
OrganismEuphorbia helioscopia (EUPHORBIACEAE)
CitationGOTTA,H: ADOLF,W: OPFERKUCH,HJ: HECKER,E:. (1984). ON THE ACTIVE PRINCIPLES OF THE EUPHORBIACEAE. IX. INGENANE TYPE DITERPENE ESTERS FROM FIVE EUPHORBIA SPECIES.. 39(5)
Amount utilized
Compound isolated
Dose amount0.22 NANOMOLS
Number14
Qualitative resultSTRONG ACTIVITY
AnimalMOUSE
Per unitEAR
Dose expressionID50(24 HR)