Experiment 1136535
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IV |
| Organism | Empty organism |
| Citation | RUCKDESCHEL,JC: DAY,R: WEISSMAN,CH: STOLBACH,LL: CREECH,RH:. (1984). CHEMOTHERAPY FOR METASTATIC NON-SMALL CELL BRONCHOGENIC CARCINOMA: CYCLOPHOSPHAMIDE,DOXORUBICIN,AND ETOPOSIDE VERSUS MITOMYCIN AND VINBLASTINE (EST 2575,GENERATION IV).. 68(11) |
| Amount utilized | |
| Compound isolated | |
| Disease | 101 PATIENTS WITH METASTATIC NON-SMALL CELL BRONCHOGENIC CARCINOMA WERE TREATED ON DAY 1 OF A 21 DAY CYCLE WITH VINCALEUKOBLASTINE AND MITOMYCIN. THERE WERE 2 COMPLETE AND 13 PARTIAL RESPONSES WITH A MEDIAN DURATION OF 87 DAYS. NEUTROPENIA RESULTED IN 1 DEATH AND OTHER TOXICITY INCLUDED INFECTION VOMITING,DIARRHEA,RESPIRATORY,NEUROLOGIC,SKIN,HEPATIC,AND UROLOGICAL PROBLEMS. |
| Dose amount | 10.0 MG |
| Number | 1 |
| Qualitative result | EQUIVOCAL |
| Animal | HUMAN ADULT |
| Per unit | SQ M BODY SURFACE |
| Dose expression | DOSE |