Experiment 1141114

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGSANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

QUINIDINE

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIP
OrganismEmpty organism
CitationTSURUO,T: LIDA,H: KITATANI,Y: YOKOTA,K: TSUKAGOSHI,S: SAKURAI,Y:. (1984). EFFECTS OF QUINIDINE AND RELATED COMPOUNDS ON CYTOTOXICITY AND CELLULAR ACCUMULATION OF VINCRISTINE AND ADRIAMYCIN IN DRUG-RESISTANT TUMOR CELLS.. 44(10)
Amount utilized
Compound isolated
DiseasePOTENTIATED THE ACTIVITY OF VINCRISTINE 100 MG/KG.
Dose amount50.0 MG
Number5
Percent yield28%
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultILS