Experiment 1143243

Worktypes

EFFECTS DUE TO A COMBINATION OF DRUGSPHARMACOLOGY OF EXTRACT - IN VIVO

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.EFFECTS MEASURED IN LIVER.

Details

PropertyValue
Pharmacology
MICROSOMAL N-DEMETHYLASE INDUCTION
Administration routeIN RATION
OrganismSenecio jacobaea (ASTERACEAE)
CitationSWICK,RA: MIRANDA,CL: CHEEKE,PR: BUHLER,DR:. (1983). EFFECT OF PHENOBARBITAL ON TOXICITY OF PYRROLIZIDINE (SENECIO) ALKALOIDS IN SHEEP.. 56(4)
Amount utilized
Compound isolated
DiseaseEFFECT SEEN AFTER 105 DAYS OF TREATMENT.DOSED WITH PHENOBARBITAL ALSO.
Dose amount20.0 % OF DIET
Number11
Qualitative resultACTIVE
AnimalLAMB
Dose expressionDOSE
ExtractFLOWERS