Experiment 115076

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC L-156602

Details

PropertyValue
Pharmacology
COMPLEMENT C5-A BINDING INHIBITION
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationHENSENS,OD: BORRIS,RP: KOUPAL,LR: CALDWELL,CG: CURRIE,SA: HAIDRI,AA: HOMNICK,CJ: HONEYCUTT,SS: LINDENMAYER,SM: SCHWARTZ,CD: WEISSBERGER,BA: WOODRUFF,HB: ZINK,DL: ZITANO,L: FIELDHOUSE,JM: ROLLINS,T: SPRINGER,MS: SPRINGER,JP:. (1991). L-156,602, A C5-A ANTAGONIST WITH A NOVEL CYCLIC HEXADEPSIPEPTIDE STRUCTURE FROM STREPTOMYCES SP. MA6348. FERMENTATION, ISOLATION AND STRUCTURE DETERMINATION.. 44(2)
Amount utilized
Compound isolated
Dose amount2.0 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalHUMAN ADULT
Dose expressionIC50