Experiment 1155474

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

TAXOL

Details

PropertyValue
Pharmacology
MICROTUBULE DISASSEMBLY INHIBITION
OrganismTaxus baccata (TAXACEAE)
CitationLATASTE,H: SENILH,V: WRIGHT,M: GUENARD,D: POTIER,P:. (1984). RELATIONSHIPS BETWEEN THE STRUCTURES OF TAXOL AND BACCATINE III DERIVATIVES AND THEIR IN VITRO ACTION ON THE DISASSEMBLY OF MAMMALIAN BRAIN AND PHYSARUM AMOEBAL MICROTUBULES.. 81(13)
Amount utilized
Compound isolated
Dose amount0.5 MICROMOLS
Number2
Qualitative resultACTIVE
AnimalPIG
Dose expressionIC50