Experiment 1158597

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE

Compounds isolated

EMBELIN

Alerts

DOSING ON DAYS 1-9.RESULTS SIGNIFICANT AT P <0.001 LEVEL.HISTOPATHOLOGY DATA ARE PRESENTED AND DISCUSSED.

Details

PropertyValue
Pharmacology
OCULAR TOXICITY
Administration routeGASTRIC INTUBATION
OrganismEmpty organism
CitationLOW,G: ROGERS,LJ: BRUMLEY,SP: EHRLICH,D:. (1985). VISUAL DEFICITS AND RETINOTOXICITY CAUSED BY THE NATURALLY OCCURRING ANTHELMINTICS, EMBELIA RIBES AND HAGENIA ABYSSINICA.. 81(2)
Amount utilized
Compound isolated
DiseaseVISUAL IMPAIRMENT WAS SEEN, WITH LOWERED ABILITY TO DETECT A BEAD MOVING INPERIPHERAL VISION AND DECREASED PERFORMANCE ON VISUAL DISCRIMINATION TESTS. NO RETINAL TOXICITY WAS NOTED.
Dose amount0.001 GM
Number1
Qualitative resultACTIVE
AnimalCHICKEN
Per unitANIMAL
Dose expressionDOSE