Experiment 1174051
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Gelsemium sempervirens (LOGANIACEAE) |
| Citation | BLAW,ME: ADKISSON,MA: LEVIN,D: GARRIOTT,JC: TINDALL,RSA:. (1979). POISONING WITH CAROLINA JESSAMINE (GELSEMIUM SEMPERVIRENS (L.) AIT.).. 94() |
| Amount utilized | |
| Compound isolated | |
| Disease | THIS ARTICLE REPORTS A CASE OF ACCIDENTAL POISONING DUE TO THE INGESTION OF APPROXIMATELY 5 BLOSSOMS OF THIS PLANT. NEUROLOGICAL SYMPTOMS INCLUDED WIDE-BASED GAIT, BILATERAL PTOSIS AND AN INABILITY TO RAISE THE CHIN FROM THE CHEST. THE PATIENT APPEARED ALERT, AND COULD FOLLOW INSTRUCTIONS BUT SHE COULD NOT SPEAK. PUPILS REACTED NORMALLY TO LIGHT. FACIAL MUSCLES WERE WEAK, AND ALL 4 EXTREMETIES SHOWED MODERATE WEAKNESS, EQUALLY DISTRIBUTED. DEEP TENDON REFLEXES WERE BRISK, BUT PLANTAR RESPONSES WERE FLEXOR. THERE WERE NO SENSORY DEFICITS. THE PATIENT WAS TREATED BY STOMACH LAVAGE AND INSTILLATION OF AN ACTIVATED CHARCOAL SLURRY IN THE STOMACH. ASCORBIC ACID WAS ADDED TO IV FLUIDS. TEN HOURS AFTER INGESTION OF THE FLOWERS, ALL ABNORMAL NEUROLOGICAL SIGNS HAD DISSAPEARED. |
| Dose amount | VAR |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN CHILD |
| Dose expression | DOSE |
| Extract | FLOWERS |