Experiment 1179741
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Areca catechu (ARECACEAE) |
| Citation | PROKOPCZYK,B: RIVENSON,A: BERTINATO,P: BRUNNEMANN,KD: HOFFMANN,D:. (1987). 3-(METHYLNITROSAMINO) PROPIONITRILE: OCCURRENCE IN SALIVA OF BETEL QUID CHEWERS, CARCINOGENICITY, AND DNA METHYLATION IN F344 RATS-1.. 47(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | 3-(METHYLNITROSAMINO)PROPIONITRILE WAS DETECTED IN THE SALIVA OF BETEL QUIDE CHEWERS AT LEVELS RANGING FROM 0.5 UG/L TO 11.4 UG/L. THIS COMPOUND DETERMINED TO BE CARCINOGENIC IN RATS. |
| Dose amount | VAR |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Dose expression | DOSE |
| Extract | SEEDS |