Experiment 1184849

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

CEPHALOSPORIUM ANTIBIOTIC 1233-A

Details

PropertyValue
Pharmacology
HMG-CO-A REDUCTASE INHIBITION
OrganismEmpty organism
CitationOMURA,S: TOMODA,H: KUMAGAI,H: GREENSPAN,MD: YODKOVITZ,JB: CHEN,JS: ALBERTS,AW: MARTIN,I: MOCHALES,S: MONAGHAN,RL: CHABALA,JC: SCHWARTZ,RE: PATCHETT,AA:. (1987). POTENT INHIBITORY EFFECT OF ANTIBIOTIC 1233A ON CHOLESTEROL BIOSYNTHESIS WHICH SPECIFICALLY BLOCKS 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE.. 40(9)
Amount utilized
Compound isolated
Dose amount>40.0 MCG
Number2
Qualitative resultINACTIVE
Per unitML
Dose expressionIC50