Experiment 1185529

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

CAMPTOTHECIN,7-ETHYL-10-(4-(1-PIPERIDINO)-1-PIPERIDINO)-CARBONYL-OXY:

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeORAL
OrganismEmpty organism
CitationKUMIMOTO,T: NITTA,K: TANAKA,T: UEHARA,N: BABA,H: TAKEUCHI,M: YOKOKURA,T: SAWADA,S: MIYASAKA,T: MUTAI,M:. (1987). ANTITUMOR ACTIVITY OF 7-ETHYL-10-[4-(1-PIPERIDINO)-1-PIPERIDINO]CARBONYLOXY-CAMPTOTHECIN, A NOVEL WATER-SOLUBLE DERIVATIVE OF CAMPTOTHECIN, AGAINST MURINE TUMORS-1.. 47(22)
Amount utilized
Compound isolated
Dose amount400 MG
Number22
Percent yield90%
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE
Expression resultTWD