Experiment 1192271

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

PROPIONIC ACID,BETA-METHYL-AMINO:

Details

PropertyValue
Pharmacology
NEUROTOXIC ACTIVITY
Administration routeINTRAGASTRIC
OrganismEmpty organism
CitationSPENCER,PS: NUNN,PB: HUGON,J: LUDOLPH,AC: ROSS,SM: ROY,DN: ROBERTSON,RC:. (1987). GUAM AMYOTROPHIC LATERAL SCLEROSIS-PARKINSONISM-DEMENTIA LINKED TO A PLANT EXCITANT NEUROTOXIN.. 237(4814)
Amount utilized
Compound isolated
DiseaseTREATED ANIMALS DEVELOPED NEURONAL DYSFUNCTION, PARKINSONIAN FEATURES, BEHAVIORAL ANOMALIES, AND DEGENERATIVE CHANGES OF MOTOR NEURONS.
Number1
Qualitative resultACTIVE
AnimalMONKEY
Dose expressionDOSE