Experiment 1212384

Worktypes

STRUCTURE-ACTIVITY RELATIONSHIP STUDIES MARKER CODEPHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SPARSOMYCIN

Details

PropertyValue
Pharmacology
PROTEIN SYNTHESIS INHIBITION
OrganismEmpty organism
CitationVAN DEN BROEK,LAGM: LAZARO,E: ZYLICZ,Z: FENNIS,PJ: MISSLER,FAN: LELIEVELD,P: GARZOTTO,M: WAGENER,DJT: BALLESTA,JPG: OTTENHEIJM,HCJ:. (1989). LIPOPHILIC ANALOGUES OF SPARSOMYCIN AS STRONG INHIBITORS OF PROTEIN SYNTHESIS AND TUMOR GROWTH: A STRUCTURE-ACTIVITY RELATIONSHIP STUDY.. 32(8)
Amount utilized
Compound isolated
DiseaseTHE EFFECT WAS MEASURED BY THE MODIFIED FRAGMENT REACTION.
Dose amount2.8 MICROMOLS
Number2
Qualitative resultACTIVE
Dose expressionED50