Experiment 1217006
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Tripterygium hypoglaucum (CELASTRACEAE) |
| Citation | QIAN,SZ: HU,YZ: WANG,SM: LUO,Y: TANG,AS: SHU,SY: ZHOU,JW: RAO,TY:. (1989). EFFECT OF TRIPTERYGIUM HYPOGLAUCUM (LEVL.) HUTCH ON THE FERTILITY OF MEN.. () |
| Amount utilized | |
| Compound isolated | |
| Disease | THERE WAS A DECREASE IN SPERM CONCENTRATION AND DECREASED PERCENTAGE OF SPERM MOTILITY WITH A MARKED LACK OF FORWARD PROGRESSION WITH SOME INCREASE IN PERCENTAGE OF ABNORMAL SPERM FORMS. HOWEVER, THE EFFECT WAS NOT TO 100% EFFECTIVENESS. THEREFORE THERE IS A QUESTION REMAINING AS TO WHETHER INFERTILITY WAS ACHIEVED OR ONLY A DECREASE IN FERTILITY. QUESTIONS THAT ARISE FROM THESE DATA ARE (A) WERE THE PARTNERS OF THESE MEN USING CONTRACEPTIVES? AND (B) COULD A HIGHER DOSE ACHIEVE AZOOSPERMIA AND/OR TOTAL LACK OF MOTILITY? |
| Dose amount | 15.0 GM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | PERSON |
| Dose expression | DOSE |
| Extract | DECOCTION |
| Gender | MALE |