Experiment 1219422

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVO

Compounds isolated

TAXOL

Details

PropertyValue
Pharmacology
OPHTHALMOLOGICAL EFFECTS
Administration routeINTRAVITREAL
OrganismEmpty organism
CitationDANIELS,SA: COONLEY,KG: YOSHIZUMI,MO:. (1990). TAXOL TREATMENT OF EXPERIMENTAL PROLIFERATIVE VITREORETINOPATHY.. 228(6)
Amount utilized
Compound isolated
DiseaseVITRECTOMIZED EYE RECEIVED INTRAVITREAL INOCULUM OF 250000 FIBROLASTS AND DOSE OF COMPOUND IN DMSO. AFTER 3 WEEKS THE INCIDENCE AND EXTENT OF TRACTIONAL RETINAL DETACHMENTS WAS SIGNIFICANTLY REDUCED.
Dose amount200.0 MILLIMOLS
Number1
Qualitative resultACTIVE
AnimalRABBIT
Dose expressionDOSE