Experiment 1220168
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Zingiber officinale (ZINGIBERACEAE) |
| Citation | IWAMA,H: AMAGAYA,S: OGIHARA,Y:. (1987). EFFECT OF SHOSAIKOTO. A JAPANESE AND CHINESE TRADITIONAL HERBAL MEDICINAL MIXTURE, ON THE MITOGENIC ACTIVITY OF LIPOPOLYSACHARIDE: A NEW PHARMACOLOGICAL TESTING METHOD.. 21(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | THE EXTRACT MIXTURE COMPOSITION CONSISTS OF THE FOLLOWING PLANTS: BUPLEURUM FALCATUM, PINELLIA TERNATA, ZINGIBER OFFICINALE, SCUTELLARIA BAICALENSIS, ZIZYPHUS VULGARIS, PANAX GINSENG, AND GLYCYRRHIZA GLABRA. THE EXTRACT MIXTURE WAS FIRST ORALLY ADMINISTERED TO MICE AND THEN THE SERUM OF THE TREATED ANIMAL WAS TESTED FOR ACTIVITY. AN INCREASE IN MITOGENIC ACTIVITY OF LIPOPOLYSACCHARIDES (LPS) WAS OBSERVED. HOWEVER, IN THE SAME EXPERIMENTAL SYSTEM WITHOUT LPS, MITOGENIC ACTION WAS NOT RECOGNIZED IN THE SPLEEN CELLS OF THE EXTRACT MIXTURE TREATED MICE. |
| Dose amount | 3.60 GM |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | CONC USED |
| Extract | HOT H2O EXT |