Experiment 1220551
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Carthamus tinctorius (ASTERACEAE) |
| Citation | WATANABE,Y: MANKU,MS: JENKINS,DK: MITCHELL,J: HORROBIN,DF:. (1988). THE EFFECTS OF SHORT TERM DIETARY SUPPLEMENTATION WITH EVENING PRIMROSE OR SAFFLOWER OIL ON FATTY ACID AND PROSTAGLANDIN RELEASE FROM PERFUSED MESENTERIC VASCULAR BEDS IN SPONTANEOUSLY HYPENTENSIVE RATS.. 8(5) |
| Amount utilized | |
| Compound isolated | |
| Disease | SPONTANEOUSLY HYPERTENSIVE RATS WERE MADE ESSENTIAL FATTY ACID DEFICIENT BY BEING FED FOR 9 WEEKS HYDROGENATED COCONUT OIL IN AN OTHERWISE FAT FREE DIET; FOR 48 HOURS THEY WERE FED GIVEN EXTRACT, AFTER WHICH THE SUPERIOR MESENTARY WAS ISOLATED. THE SUPERIOR MESENTERIC ARTERY PERFUSATE WAS ASSAYED FOR RELEASE OF DIHOMO-GAMMA LINOLENIC ACID. THE VALUES WERE DECREASED COMPARED TO THOSE OF WISTAR KYOTO RATS. |
| Dose amount | 10.0 % OF DIET |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Dose expression | DOSE |
| Extract | SEED OIL |