Experiment 1223681

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

CAMPTOTHECIN,7-ETHYL-10-(4-(1-PIPERIDINO)-1-PIPERIDINO)-CARBONYL-OXY:*

Alerts

DOSING ON DAYS 1-5.

Details

PropertyValue
Pharmacology
METASTASIS INHIBITION
Administration routeIV
OrganismEmpty organism
CitationMATSUZAKI,T: YOKOKURA,T: MUTAI,M: TSURUO,T:. (1988). INHIBITION OF SPONTANEOUS AND EXPERIMENTAL METASTASIS BY A NEW DERIVATIVE OF CAMPTOTHECIN, CPT-11, IN MICE.. 21(4)
Amount utilized
Compound isolated
DiseaseTHERE WAS A 75% REDUCTION IN PULMONARY METASTASIS.
Dose amount200.0 MG
Number2
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE