Experiment 1225675

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOEFFECTS DUE TO A COMBINATION OF DRUGS

Compounds isolated

DIOSMIN

Alerts

A MIXTURE OF PURE COMPOUNDS WAS USED TO OBTAIN THE REPORTED EFFECT.

Details

PropertyValue
Pharmacology
PROSTAGLANDIN INHIBITION
Administration routeGASTRIC INTUBATION
OrganismEmpty organism
CitationDAMON,M: FLANDRE,O: MICHEL,F: PERDRIX,L: LABRID,C: CRASTES DE PAULET,A:. (1987). EFFECT OF CHRONIC TREATMENT WITH A PURFIED FLAVONOID FRACTION ON INFLAMMATORY GRANULOMA IN THE RAT.. 37(10)
Amount utilized
Compound isolated
DiseaseMIXTURE OF 90% DIOSMIN AND 10% HESPERIDIN WAS USED AGAINST SPONGE-INDUCED GRANULOMA. PGE2 LEVEL OF TREATED RATS WAS SIGNIFICANTLY LOWER THAN UNTREATED CONTROLS THROUGH 16 DAYS AFTER SPONGE IMPLANTATION. DOSING BEGAN 15 DAYS PREOPERATIVELY.
Dose amount100.0 MG
Number2
Qualitative resultACTIVE
AnimalRAT
Per unitKG
Dose expressionDOSE