Experiment 1225685
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | GASTRIC INTUBATION |
| Organism | Empty organism |
| Citation | DAMON,M: FLANDRE,O: MICHEL,F: PERDRIX,L: LABRID,C: CRASTES DE PAULET,A:. (1987). EFFECT OF CHRONIC TREATMENT WITH A PURFIED FLAVONOID FRACTION ON INFLAMMATORY GRANULOMA IN THE RAT.. 37(10) |
| Amount utilized | |
| Compound isolated | |
| Disease | MIXTURE OF 90% DIOSMIN AND 10% HESPERIDIN WAS USED AGAINST SPONGE-INDUCED GRANULOMA. DOSING BEGAN 15 DAYS BEFORE SPONGE IMPLANTATION. 30 DAYS POST-OPERATIVELY, TREATED ANIMALS HAD FEWER POLYORPHS AND MACROPHAGES IN THE GRANULOMAS; THE NEWLY FORMED VASCULAR NETWORK WAS SMALLER AND DEVELOPMENT TOWARDS CHRONIC GRANULOMA WAS RETARDED OR STOPPED. |
| Dose amount | 100.0 MG |
| Number | 6 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |