Experiment 1227219
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Empty organism |
| Citation | EMEROLE,G: THABREW,MI: ANOSA,V: OKORIE,DA:. (1981). STRUCTURE-ACTIVITY RELATIONSHIP IN THE TOXICITY OF SOME NATURALLY OCCURRING COUMARINS-CHALEPIN, IMPERATORIN AND OXYPEUCEDANINE.. 20(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | DOSING ON TWO CONSECUTIVE DAYS CAUSED GENERALIZED NECROSIS OF HEPATOCYTES IN ANIMALS WHO DIED WITHIN 48 HOURS. AT 8 WEEKS, THE SURVIVORS ALSO SHOWED NECROSIS, BUT IT WAS LESS SEVERE. |
| Dose amount | 100.0 MG |
| Number | 1 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |