Experiment 1227245
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Stigmatella aurantiaca (CYSTOBACTERACEAE) |
| Citation | THERBACH,G: KUNZE,B: REICHENBACH,H: HOFLE,G:. (1984). THE MODE OF ACTION OF STIGMATELLIN, A NEW INHIBITOR OF THE CYTOCHROME B-C SEGMENT OF THE RESPIRATORY CHAIN.. 762(2) |
| Amount utilized | |
| Compound isolated | |
| Disease | INHIBITION OF NADH OXIDATION IN SUBMITOCHONDRAIL PARTICLES WAS ASSAYED. THE FLOW OF ELECTRONS DOWN THE RESPIRATORY CHAIN WAS BLOCKED AT THE CYTOCHROME B-C1 STEP. |
| Dose amount | 15.0 NANOMOLS |
| Number | 3 |
| Qualitative result | ACTIVE |
| Animal | CELL CULTURE |
| Dose expression | IC50 |