Experiment 1244037

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOTOXICITY MARKER CODE

Compounds isolated

LASIOCARPINE

Details

PropertyValue
Pharmacology
HEPATOTOXIC ACTIVITY
Administration routeGASTRIC INTUBATION
OrganismHeliotropium europaeum (BORAGINACEAE)
CitationSCHOENTAL,R: MAGEE,PN:. (1957). CHRONIC LIVER CHANGES IN RATS AFTER A SINGLE DOSE OF LASIOCARPINE, A PYRROLIZIDINE (SENECIO) ALKALOID.. 74()
Amount utilized
Compound isolated
Disease2/17 DIED WITHIN 3 MONTHS AFTER A SINGLE DOSE 15/17 SURVIVORS AFTER 13 MONTHS LIVER LESIONS DEMONSTRATED HISTOLOGICALLY
Dose amount50-74 MG
Number1
Qualitative resultACTIVE
AnimalRAT(IMMATURE)
Per unitKG
Dose expressionDOSE
GenderGIVEN TO BOTH SEXES