Experiment 1307649

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

IMBERBIC ACID,23-ACETOXY-3-BETA-ACETYL-29-METHYL ESTER: 1-O-[ALPHA-L-RHAMNOPYRANOSIDE]:IMBERBIC ACID,23-ACETOXY-29-METHYL-ESTER: 1-O-[ALPHA-L-RHAMNOPYRANOSIDE]:IMBERBIC ACID,3-BETA-ACETYL: 23-O-[ALPHA-L-(3'-4'-DIACETYL)-RHAMNOPYRANOSIDE:IMBERBIC ACID,3-BETA-ACETYL-29-METHYL ESTER: 23-O-[ALPHA-L-(4'-ACETYL)-RHAMNOPYRANOSIDE:IMBERBIC ACID,23-ACETOXY-3-BETA:23-O-[ALPHA-L-(2'-4'-DIACETYL)-RHAMNOPYRANOSIDEIMBERBIC ACID,23-ACETOXY-3-BETA-ACETYL: 1-O-[ALPHA-L-RHAMNOPYRANOSIDE]:LANTADENE BLANTADENE ALANTADENE A,DIHYDRO:IMBERBIC ACID,23-ACETOXY-29-METHYL ESTER:IMBERBIC ACID,3-BETA-ACETYL: 23-O-[ALPHA-L-(4'-ACETYL)-RHAMNOPYRANOSIDE:

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
BCL (ANTI-APOPTOTIC) PROTEIN BINDING INHIBITION
OrganismCombretum sundaicum (COMBRETACEAE)
CitationLITAUDON,M: JOLLY,C: LE CALLONEC,C: CUONG,DD: RETAILLEAU,P: NOSJEAN,O: NGUYEN,VH: PFEIFFER,B: BOUTIN,JA: GUERITTE,F:. (2009). CYTOTOXIC PENTACYCLIC TRITERPENOIDS FROM COMBRETUM SUNDAICUM AND LANTANA CAMARA AS INHIBITORS OF BCL-XL/BAKBH3 DOMAIN PEPTIDE INTERACTION. 72(7)
Amount utilized
Compound isolated
Dose amount>100 MICROMOLS
Number11
Qualitative resultINACTIVE
Dose expressionIC50