Experiment 1309021

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

MYCALAZAL 19MYCALAZAL 15MYCALENITRILE-2MYCALENITRILE-12PYRROLE-2-CARBOXALDEHYDE,5-PENTADECYL:MYCALENITRILE-11MYCALENITRILE-10MYCALENITRILE-9PYRROLE-2-CARBOXALDEHYDE,5-HEXADECYL:MYCALENITRILE-4MYCALENITRILE-14

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
HYPOXIA-INDUCIBLE FACTOR-1 INHIBITION
OrganismMycale species (MYCALIDAE)
CitationMAO,S: LIU,Y: MORGAN,JB: JEKABSONS,MB: ZHOU,Y: NAGLE,DG:. (2009). LIPOPHILIC 2,5-DISUBSTITUTED PYRROLES FROM THE MARINE SPONGE MYCALE SP. INHIBIT MITOCHONDRIAL RESPIRATION AND HIF-1 ACTIVATION. 72(11)
Amount utilized
Compound isolated
Dose amount30 MICROMOLS
Number26
Qualitative resultINACTIVE
AnimalCELL CULTURE
Dose expressionCONC USED