Experiment 1311788

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SCALAR-16-EN-22-OIC ACID,24-METHYL-12-24-25-TRIOXO:SCALAR-16-EN-25-AL,22-HYDROXY-24-METHYL-12-24-DIOXO:FUROSPONGOLIDE

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
INHIBITION OF HYPOXIA-INDUCIBLE FACTOR 1 (HIF-1) ACTIVATION
OrganismLendenfeldia species (DYSIDEIDAE)
CitationLIU,Y: LIU,R: MAO,S: MORGAN,JB: JEKABSONS,MB: ZHOU,Y: NAGLE,DG:. (2008). MOLECULAR-TARGETED ANTITUMOR AGENTS. 19. FUROSPONGOLIDE FROM A MARINE LENDENFELDIA SP. SPONGE INHIBITS HYPOXIA-INDUCIBLE FACTOR-1 ACTIVATION IN BREAST TUMOR CELLS. 71(11)
Amount utilized
Compound isolated
Dose amount<5 MICROMOLS
Number5
Qualitative resultACTIVE
AnimalCELL CULTURE
Dose expressionIC50