Experiment 1312406

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

SALINOSPORAMIDE A

Alerts

SEE ARTICLE FOR OTHER TEST RESULTS.

Details

PropertyValue
Pharmacology
CYTOTOXIC ACTIVITY
OrganismSalinispora tropica nps000465 (MICROMONOSPORACEAE)
CitationREED,KA: MANAM,RR: MITCHELL,SS: LU,JL TEISAN,S: CHAO,TH: DEYANAT-YAZDI,G: NEUTEBOOM,STC: LAM,KS: POTTS,BCM:. (2007). SALINOSPORAMIDES D-J FROM THE MARINE ACTINOMYCETE SALINISPORA TROPICA, BROMOSALINOSPORAMIDE, AND THIOESTER DERIVATIVES ARE POTENT INHIBITORS OF THE 20S PROTEASOME. 70(2)
Amount utilized
Compound isolated
Dose amount<1 MICROMOLS
Number11
Qualitative resultSTRONG ACTIVITY
AnimalCELL CULTURE
Dose expressionIC50