Experiment 1317334
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | INTRAGASTRIC |
| Organism | Bupleurum chinense (APIACEAE) |
| Citation | SU,GY: YANG,JY: WANG,F: MA,J: ZHANG,K: DONG,YX: SONG,SJ: LU,XM: WU,CF:. (2014). ANTIDEPRESSANT-LIKE EFFECTS OF XIAOCHAIHUTANG IN A RAT MODEL OF CHRONIC UNPREDICTABLE MILD STRESS. 152(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | EFFECT OF XCHT ON HIPPOCAMPAL NEUROTRANSMITTER UPREGULATION (5-HT AND DOPAMINE) IN FOOD AND WATER-DEPRIVED ANIMALS (CUMS MODEL). FOUR WEEK DOSING. XCHT IS COMPOSED OF 12 G OF RADIX BUPLEURI (FAMILY: UMBELLIFERAE; LATIN NAME: BUPLEURUM CHINENSE DC.), 9 G OF RADIX SCUTELLARIAE (FAMILY: LABIATAE; LATIN NAME: SCUTELLARIA BAICALENSIS GEORGI), 9 G OF GINSENG (FAMILY: ARALIACEAE; LATIN NAME: PANAX GINSENG C.A. MEYER), 9 G OF RHIZOMA PINELLIAE [FAMILY: ARACEAE; LATIN NAME: PINELLIA TERNATA (THUNB.) BREIT.], 6 G OF RADIX GLYCYRRHIZAE (FAMILY: LEGUMINOSAE; LATIN NAME: GLYCYRRHIZA URALENSIS FISCH.), 6 G OF RHIZOMA ZINGIBERIS RECENS (FAMILY: ZINGIBERACEAE; LATIN NAME: ZINGIBER OFFICINALE ROSC.) AND 4 PIECES (ABOUT 9 G) OF FRUCTUS JUJUBAE (FAMILY: RHAMNACEAE; LATIN NAME: ZIZIPHUS JUJUBA MILL.). TRIPLE DECOCTION OF XCHT WAS THEN LYOPHILIZED AND ADMINISTERED TO THE TEST ANIMALS, |
| Dose amount | >5 GM |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | RAT |
| Per unit | KG |
| Dose expression | DOSE |
| Extract | DECOCTION |
| Gender | MALE |