Experiment 131970

Worktypes

PHARMACOLOGY OF COMPOUND - IN VIVOANTICANCER AND/OR CYTOTOXICITY MARKER CODE

Compounds isolated

SPIRO(2.5)-OCT-6-YL-4-5-4(3)-5(S)-DIHYDROXY-HEX-TRANS-2-ENOATE,5-METHOXY-4-(2(R)-METHYL-3-(3(R)-METHYL-2-BUTENYL)OXIRANYL)-1-OXA:

Details

PropertyValue
Pharmacology
ANTITUMOR ACTIVITY
Administration routeIV
OrganismScolecobasidium arenarium (HYPHOMYCETES)
CitationOTSUKA,T: SHIBATA,T: TSURUMI,Y: TAKASE,S: OKUHARA,M: TERANO,H: KOHSAKA,M: IMANAKA,H:. (1992). A NEW ANGIOGENESIS INHIBITOR, FR-111142.. 45(3)
Amount utilized
Compound isolated
DiseaseMICE WERE DOSED ON DAYS 1-4 AND 7-10.
Dose amount0.3 MG
Number16
Qualitative resultACTIVE
AnimalMOUSE
Per unitKG
Dose expressionDOSE