Experiment 1319879
Compounds isolated
Alerts
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | SC |
| Organism | (12) |
| Citation | SHU,H: HAYASHIDA,M: ARITA,H: HUANG,WQ: XIAO,LS: CHIBA,S: SEKIYAMA,H: HANAOKA,K:. (2008). HIGH DOSES OF PROCESSED ACONITI TUBER INHIBIT THE ACUTE BUT POTENTIATE THE CHRONIC ANTINOCICEPTION OF MORPHINE. 119() |
| Amount utilized | |
| Compound isolated | |
| Disease | 10 DAY DOSING. BASELINE OF ANTINOCICEPTIVE ACTIVITY ON MORPHINE ALONE WAS SIGNIFICANTLY REDUCED BY DAY 4 OF STUDY (DRUG TOLERANCE). COADMINISTRATION WITH ACONITUM CARMICHAELII INHIBITED THE ANTINOCICEPTIVE INHIBITORY EFFECT (MORPHINE TOLERANCE INHIBITION). |
| Dose amount | 10 MG |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | MOUSE |
| Per unit | KG |
| Dose expression | DOSE |
| Gender | MALE |