Experiment 1321784
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | IP |
| Organism | Zingiber officinale (ZINGIBERACEAE) |
| Citation | DARVISHZADEH-MAHANI,F: ESMAEILI-MAHANI,S: KOMEILI,G: SHEIBANI,V: ZARE,L:. (2012). GINGER (ZINGIBER OFFICINALE ROSCOE) PREVENTS THE DEVELOPMENT OF MORPHINE ANALGESIC TOLERANCE AND PHYSICAL DEPENDENCE IN RATS. 141() |
| Amount utilized | |
| Compound isolated | |
| Disease | 8 DAY STUDY. GINGER EXTRACT WAS COADMINISTERED WITH MORPHINE (DOSE INCREASED FROM 2 DAILY DOSES AT 2.5 MG/KG EACH, WITH DAILY DOSE INCREASED TO 2X 50 MG/KG AT DAY 7 ). GINGER REDUCED ANTINOCICEPTIVE MORPHINE TOLERANCE (CHRONIC DOSING MODEL) AFTER THE THIRD DAY OF MORPHINE ADMINISTRATION. |
| Number | 3 |
| Animal | RAT |
| Extract | ETOH(80%)EXT |