Experiment 1323033
Worktypes
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Administration route | ORAL |
| Organism | Glycyrrhiza glabra (FABACEAE) |
| Citation | AGARWAL,A: GUPTA,D: YADAV,G: GOYAL,P: SINGH,PK: SINGH,U:. (2009). AN EVALUATION OF THE EFFICACY OF LICORICE GARGLE FOR ATTENUATING POSTOPERATIVE SORE THROAT: A PROSPECTIVE, RANDOMIZED, SINGLE-BLIND STUDY. 109(1) |
| Amount utilized | |
| Compound isolated | |
| Disease | THIS PROSPECTIVE, RANDOMIZED, SINGLE-BLIND, PLACEBO CONTROLLED STUDY EVALUATED FORTY ADULTS (18–60 YR)OF EITHER SEX, UNDERGOING ELECTIVE LUMBER LAMINECTOMY. THEY WERE RANDOMIZED INTO TWO GROUPS OF 20 EACH. GROUP C: RECEIVED WATER; GROUP L: RECEIVED 0.5 G LICORICE IN WATER.THE INCIDENCE AND SEVERITY OF POST AT REST AND ON SWALLOWING AND SIDE EFFECTS WERE ASSESSED AT 0, 2, 4, AND 24 H, POSTOPERATIVELY. SEVERITY OF POST WAS ASSESSED BY VISUAL ANALOG SCALE (BETWEEN 0 AND 100 MM; WHERE 0 MEANS NO SORE THROAT AND 100 MEANS WORST IMAGINABLE SORE THROAT). POSTEXTUBATION COUGH WAS ASSESSED IMMEDIATELY AFTER TRACHEAL EXTUBATION. POST (INCIDENCE AND SEVERITY) WAS REDUCED IN THE GROUP L COMPARED WITH GROUP C AT REST AND ON SWALLOWING FOR ALL TIME POINTS CONCLUSION: LICORICE GARGLE PERFORMED 5 MIN BEFORE ANESTHESIA IS EFFECTIVE IN ATTENUATING THE INCIDENCE AND SEVERITY OF POST. |
| Dose amount | 16 MG |
| Number | 0 |
| Qualitative result | ACTIVE |
| Animal | HUMAN ADULT |
| Per unit | ML |
| Dose expression | DOSE |
| Extract | DECOCTION |