Experiment 133353
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Streptomyces misakiensis (STREPTOMYCETACEAE) |
| Citation | KOJIRI,K: IHARA,M: NAKAJIMA,S: KAWAMURA,K: FUNAISHI,K: YANO,M: SUDA,H:. (1991). ENDOTHELIN-BINDING INHIBITORS, BE-18257-A AND BE-18257-B. I. TAXONOMY, FERMENTATION, ISOLATION AND CHARACTERIZATION.. 44(12) |
| Amount utilized | |
| Compound isolated | |
| Disease | COMPOUND ANTAGONIZED BINDING OF ENDOTHELIN-1 TO RECEPTORS IN AORTIC SMOOTH MUSCLE MEMBRANES. |
| Dose amount | 3.0 MICROMOLS |
| Number | 2 |
| Qualitative result | ACTIVE |
| Animal | PIG |
| Dose expression | IC50 |