Experiment 134959

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

ANTIBIOTIC WF-11605

Details

PropertyValue
Pharmacology
LEUKOTRIENE RECEPTOR BINDING EFFECT
OrganismMycelia sterilia (AGONOMYCETES)
CitationTSUJII,E: TSURUMI,Y: MIYATA,S: FUJIE,K: KAWAKAMI,A: OKAMOTO,M: OKUHARA,M:. (1992). WF11605, AN ANTAGONIST OF LEUKOTRIENE B-4 PRODUCED BY A FUNGUS. I. PRODUCING STRAIN, FERMENTATION, ISOLATION AND BIOLOGICAL ACTIVITY.. 45(5)
Amount utilized
Compound isolated
DiseaseVS.LTB4-INDUCED DEGRANULATION IN CYTOCHALASIN-TREATED CELLS.
Dose amount1.8 MICROMOLS
Number4
Qualitative resultACTIVE
AnimalRABBIT
Dose expressionIC50