Experiment 135331

Worktypes

PHARMACOLOGY OF COMPOUND - IN VITRO

Compounds isolated

STREPTOMYCES ANTIBIOTIC WS-7338-D

Details

PropertyValue
Pharmacology
ENDOTHELIN-1 RECEPTOR BINDING
OrganismStreptomyces species (STREPTOMYCETACEAE)
CitationMIYATA,S: HASHIMOTO,M: MASUI,Y: EZAKI,M: TAKASE,S: NISHIKAWA,M: KIYOTO,S: OKUHARA,M: KOHSAKA,M:. (1992). WS-7338, NEW INDOTHELIN RECEPTOR ANTAGONISTS ISLOATED FROM STREPTOMYCES SP. NO. 7338. I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.. 45(1)
Amount utilized
Compound isolated
Dose amount43.0 MICROMOLS
Number22
Qualitative resultACTIVE
AnimalPIG
Dose expressionIC50