Experiment 135488
Worktypes
Compounds isolated
Details
| Property | Value |
|---|---|
| Pharmacology | |
| Organism | Streptomyces species (STREPTOMYCETACEAE) |
| Citation | MIYATA,S: OHHATA,N: MURAJ,H: MASUI,Y: EZAKI,M: TAKASE,S: NISHIKAWA,M: KIYOTO,S: OKUHARA,M: KOHSAKA,M:. (1992). WS009 A AND B, NEW ENDOTHELIN RECEPTOR ANTIAGONISTS ISOLATED FROM STREPTOMYCES SP. NO.89009. I. TAXONOMY, FERMENTATION, ISOLATION, PHYSICO-CHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES.. 45(7) |
| Amount utilized | |
| Compound isolated | |
| Disease | ENDOTHELIAL-2-RECEPTOR BINDING INHIBITION WAS ASSAYED. PORCINE AORTA MEMBRANES WERE USED. |
| Dose amount | 0.80 MICROMOLS |
| Number | 12 |
| Qualitative result | ACTIVE |
| Dose expression | IC50 |